CVS Second Booster Shot The CDC has expanded eligibility for a second booster shot for adults age 50+ as early as four months after their first booster shot of any COVID-19 vaccine.

Before we schedule your booster vaccine(s)

For the safety of other customers and our employees, let’s first get these familiar questions out of the way.

CVS Second Booster Shot
CVS Second Booster Shot

Do you currently or have you in the past 14 days, had a fever, chills, cough, shortness of breath, difficulty breathing, fatigue, muscle or body aches, headache, new loss of taste or smell, sore throat, nausea, vomiting, or diarrhea?

Everything you need to know about the COVID-19 vaccine

Getting vaccinated

  • Vaccines are safe and effective in preventing serious illness caused by COVID-19. 
  • The FDA has approved COVID-19 vaccines from Pfizer-BioNTech for age 16+ and Moderna for age 18+.
  • Emergency Use Authorization (EUA) remains in place for the Johnson & Johnson (Janssen) vaccine for age 18+ and the Pfizer-BioNTech vaccine for ages 5-15. 

Boosters are worth a shot

CDC recommended booster shots can help provide continued, long-lasting protection against severe complications, hospitalization and death from COVID-19 for select individuals.

You can choose which booster you receive, as the CDC’s guidelines now allow you to mix and match dosing for booster shots.

Protecting our youth

Pfizer-BioNTech vaccine has been shown to be about 91% effective in children ages 5 to 11 and the CDC has recommended its use. Trials showed the vaccine was safe, well tolerated and produced a robust antibody response.

Vaccine side effects

  • Minor side effects are normal signs that your body is building protection.
  • Common side effects may include pain at the injection site, tiredness, headache, muscle and joint pain or chills and fever.
  • The vaccine does not contain the virus so it cannot give you COVID-19.

Why get the COVID-19 vaccine from CVS Health®?

  • CVS Health has administered over 34 million COVID-19 vaccines to date
  • We have years of experience safely administering vaccines, such as those for flu, shingles and pneumonia
  • We offer easy and convenient online scheduling options so you can schedule both required doses at the same time

CVS Second Booster Shot Frequently Asked Questions

Which vaccines have been FDA approved for COVID-19?

The FDA has rigorous scientific and regulatory processes in place to facilitate development and ensure the safety, effectiveness and quality of COVID-19 vaccines. As of August 23, 2021, the FDA has issued full approval of the Pfizer-BioNTech vaccine for use with individuals ages 16 and over, and as of January 31, 2022 has issued full approval for the Moderna vaccine for use in individuals ages 18 and over.
The previously issued Emergency Use Authorizations (EUA) for COVID-19 vaccines manufactured by Pfizer (for ages 5-15 years) and Johnson & Johnson’s Janssen remain in effect. An EUA gives the FDA authority to allow unapproved medical products to be used in emergencies when no approved alternatives are available. Other COVID-19 vaccines are in development and will be reviewed by the FDA under EUA. Find the current status of the vaccine approvals and EUAs. Find the current status of the vaccine approvals and EUAs.Opens FDA web site in a new window

What is the role of CVS Health in administering COVID-19 vaccines?

CVS Health has administered more than 32 million COVID-19 tests and 34 million COVID-19 vaccines. The Company maintains a strong commitment to vaccine and testing equity and continues to optimize site locations and targeted outreach initiatives in order to reach vulnerable populations.

Who qualifies for a booster shot?

Following guidelines set by ACIP and the CDC all individuals who are over the age of 18 are eligible to receive a Moderna or Pfizer-BioNTech COVID-19 booster shot at least five months after their primary two-dose vaccination series.

The FDA and CDC also authorized the administration of a booster dose of the Pfizer-BioNTech vaccine for patients ages 12-17 years, five months after receiving the second dose of their primary COVID-19 vaccination series.

Eligible individuals do not need to receive a booster shot that matches the formulation of their primary series. If individuals choose a booster dose that differs from their primary vaccine series, the manufacturers recommend individuals should check with their health care provider regarding the timing of the booster dose.

Additionally, individuals who are 18 years and old and received the Johnson & Johnson (Janssen) COVID-19 vaccine may receive a single booster does of Johnson & Johnson (Janssen), Moderna, or Pfizer-BioNTech COVID-19 vaccine at least two months after receiving their primary vaccination.

Patients who received a Johnson & Johnson (Janssen) COVID-19 vaccine and prefer to receive a Johnson & Johnson (Janssen) booster are encouraged to contact their primary care provider for best next steps or refer to for more information.

Can eligible populations receive their booster at CVS?

Moderna and Pfizer-BioNTech booster shots for eligible individuals 18+ are available at select CVS Pharmacy and MinuteClinic locations.

In addition, as of Tuesday, January 4, individuals ages 12-17 years are eligible to receive the Pfizer-BioNTech COVID-19 booster shot at CVS Pharmacy locations currently carrying this vaccine. A parent or legal guardian must complete the online registration on for minors up to age 17. Teens 16 and older do not need to be accompanied by an adult to their vaccination appointment, unless required by local or state law.

Are patients eligible for a 4th COVID-19 vaccine dose?

At this time, only moderately or severely immunocompromised patients who received Moderna or Pfizer for their primary series are eligible for a 4th dose, which would be their 1st booster. Eligible patients should receive the booster five months after completing the primary three-dose series, according to CDC guidance.

Is the booster covered by insurance?

Yes, the booster is available at no cost to any eligible patient either through insurance or a federal program for the uninsured.